drugset / Trial / NCT03917459
COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study was to determine the effect of sacubitril/valsartan (LCZ696) vs. Enalapril on improvement in erectile function and ability in male patients with chronic heart failure with reduced ejection fraction and erectile dysfunction.
Timeline
- Start
- 2019-04-16
- Primary completion
- 2021-05-25
- Completion
- 2021-05-25
Outcome
Missed primary endpoint
registry analysis (other test); LCZ696 vs Enalapril; p = 0.3432; LS mean of treatment difference 2.9 (95% CI -3.29 to 9.01) NCT03917459 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Enalapril | Other / unclassified | 10 mg | — |
| Subject | LCZ696 | Unknown | 200 mg | — |