drugset / Trial / NCT03918187

Intrathecal Nalbuphine Versus Midazolam in Cesarean Section

NCT03918187

Phase 1 Completed 90 enrolled Zagazig University
RandomizedParallel-groupDouble-blindHealth-services research

Summary

Adequate pain management is important to facilitate the functional recovery and enable the patients for rapid rehabilitation of normal activity . Various adjuvants were being used with intrathecal bupivacain to prolong \& improve postoperative pain relief in patients undergoing cesarean section . The aim of this study was to compare intrathecal nalbuphine versus intrathecal midazolam in patient undergoing cesarean section. The investigators primary aims were to compare the characteristics of sensory and motor block, the effective analgesic time, and analgesic requirement. Secondary aims were to compare the side effects, sedation score and apgare score.

Timeline

Start
2019-04-10
Primary completion
2019-08-30
Completion
2019-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Midazolam Small molecule 2.5 mg Intrathecal
Comparator Nalbuphine Small molecule 1 mg Intrathecal
Background Bupivacaine Other / unclassified 12.5 mg Intrathecal

Indications

No indication recorded.