drugset / Trial / NCT03927209
A Study in Healthy Men to Test the Effects of Different Doses of BI 1467335 on MAO-B Activity in the Brain.
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The main objective of this trial is to investigate the effect of multiple oral dosing of high dose BI 1467335 over 28 days and multiple oral dosing of low dose BI 1467335 over 42 days on MAO-B occupancy in the brain compared to baseline using \[11C\]-L-deprenyl-D2 PET tracer in healthy male subjects.
Timeline
- Start
- 2019-06-06
- Primary completion
- 2019-11-22
- Completion
- 2019-11-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BI 1467335 | Unknown | — | Oral |
Indications
No indication recorded.