drugset / Trial / NCT03936140

The Effect of Iloprost on Oxygenation During One-lung Ventilation for Lung Surgery

NCT03936140

RandomizedParallel-groupDouble-blindTreatment

Summary

During one-lung ventilation in patients undergoing thoracic surgery, the persistent flow in the non-ventilated lung increases intrapulmonary shunt and decreases systemic arterial oxygenation. This prospective, randomized, double blind study was conducted to evaluate the effects of inhaled iloprost during one-lung ventilation on arterial oxygenation and shunt fraction during thoracic surgery.

Timeline

Start
2018-01-04
Primary completion
2018-10-24
Completion
2018-10-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Iloprost Other / unclassified 10 ug Inhaled
Subject Iloprost Other / unclassified 20 ug Inhaled

Indications