drugset / Trial / NCT03949517

68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU Therapy

NCT03949517

Phase 1/2 Completed 14 enrolled Andrei Iagaru General Electric · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is being conducted to determine whether the combination of imaging agents 68-Ga RM2 and 68-Ga PMSA11 is better at assessing response to high intensity focused ultrasound (HIFU) or high dose rate (HDR) local therapy than standard imaging or biopsy in patients with known prostate cancer.

Timeline

Start
2019-04-09
Primary completion
2022-03-07
Completion
2022-03-07

Drugs

EvaluationDrugModalityDoseRoute
Subject 68Ga-PSMA-11 Diagnostic / imaging agent 111 mbq Intravenous
Subject 68Ga-PSMA-11 Diagnostic / imaging agent 259 mbq Intravenous
Subject 68Ga-RM2 Diagnostic / imaging agent 140 mbq Intravenous

Indications