drugset / Trial / NCT03957876

CPX-351 Therapy for MDS After Hypomethylating Agent Failure

NCT03957876

Phase 2 Terminated 4 enrolled Case Comprehensive Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy of treatment with CPX-351 (an FDA approved drug for the treatment of AML) in individuals with MDS while using a new stratification tool to predict outcomes of participants following HMA failure. This approach is intended to gain a better understanding and insight into identifying new opportunities for drug approvals in this setting.

Timeline

Start
2019-07-25
Primary completion
2022-12-20
Completion
2022-12-20

Drugs

EvaluationDrugModalityDoseRoute
Subject CPX-351 Other / unclassified 15.4 mg/m2 Intravenous