drugset / Trial / NCT03961828
Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Patients with transfusion dependent Beta Thalassemia suffer from a high incidence of Hepatitis C infection especially in developed countries as Egypt. In our patients we also found a high correlation between hepatitic C infection and Liver fibrosis. in this study we offer our patients treatment with Direct antiviral drugs and assessed the degree of fibrosis before and after treatment. We tested Hyalornic acid as a predictor of the degree of fibrosis before and after treatment.
Timeline
- Start
- 2017-10-01
- Primary completion
- 2018-12-31
- Completion
- 2019-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ledipasvir | Small molecule | 90 mg | Oral |
| Subject | Sofosbuvir | Small molecule | 400 mg | Oral |