drugset / Trial / NCT03974243

Chiauranib in Combination With Chidamide in Patients With Relapsed/Refractory Non-Hodgkin's Lymphoma

NCT03974243

Phase 1/2 Completed 9 enrolled Chipscreen Biosciences, Ltd.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this dose-escalation study is to assess the safety and tolerability of treatment with Chiauranib and Chidamide administered orally over a range of doses in patients with relapsed or refractory non-Hodgkin's lymphoma, in the meantime, exploring the pharmacodynamic profile and latent biomarkers accompany with Chiauranib and Chidamide , as well as the relevancy of which and clinical benefit.

Timeline

Start
2019-07-11
Primary completion
2021-12-31
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject IBCASERTIB Small molecule 50 mg Oral
Subject Tucidinostat Small molecule Oral

Indications