drugset / Trial / NCT03989414

A Study to Determine the Recommended Dose and Regimen and to Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)

NCT03989414

Phase 1/2 Active not recruiting 424 enrolled Celgene Corporation
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.

Timeline

Start
2019-09-30
Primary completion
2026-11-30
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Mezigdomide Small molecule
Background Bortezomib Small molecule
Background Carfilzomib Other / unclassified
Background Daratumumab Monoclonal antibody
Background Dexamethasone Small molecule
Background Elotuzumab Monoclonal antibody
Background Isatuximab Monoclonal antibody

Indications