drugset / Trial / NCT03989778
Vitamin D and Polycystic Ovarian Syndrome (PCOS)
RandomizedSingle-groupOpen-labelTreatment
Summary
Primary Objectives: To evaluate the efficacy of metformin and Vitamin D supplementation on serum insulin and serum androgen levels (Total testosterone, Steroid Hormone Binding Globulin, Free Androgen Index) levels compared metformin alone in infertile Poly cystic ovarian females of reproductive age group. Secondary Objectives: To measure change in endometrial thickness/number of follicles and follicular size by day 12 trans-vaginal ultrasound in the intervention group i.e. combination of metformin and vitamin D supplementation
Timeline
- Start
- 2023-02-01
- Primary completion
- 2025-06-30
- Completion
- 2025-07-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Vitamin D | Other / unclassified | 50000 iu | — |
| Background | Metformin | Small molecule | — | — |