Intravenous Infusion of Lidocaine in ERCP

Phase 4 Unknown 40 enrolled Shandong University

RandomizedParallel-groupTriple-blindHealth-services research

Summary

Intravenous infusion of lidocaine significantly reduces propofol dose for ERCP and improve patients' recovery after ERCP.

Timeline

Start: 2019-05-15
Primary completion: 2019-10-15
Completion: 2019-11-15

Outcome

Met primary endpoint

paper Compared with the control group, propofol requirements were reduced by 33.8% in the lidocaine group (212.0 ± 118.2 mg vs 320.0 ± 189.6 mg, P = .023). PMID 32156544 ↗

Publications

Liu J, Liu X, Peng LP, Ji R, Liu C, Li YQ. Efficacy and safety of intravenous lidocaine in propofol-based sedation for ERCP procedures: a prospective, randomized, double-blinded, controlled trial. Gastrointest Endosc. 2020 Aug;92(2):293-300. doi: 10.1016/j.gie.2020.02.050. Epub 2020 Mar 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	2 mg/kg	Intravenous

Indications

No indication recorded.