drugset / Trial / NCT04000308

QLB vs. Wound Infiltration in Cesarean Section

NCT04000308

Completed 116 enrolled University Medical Centre Ljubljana
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Effective postoperative analgesia after cesarean section (CS) is important because it enables early ambulation and facilitates breast-feeding. A 2009 Cochrane review concluded that wound infiltration with local analgesic after CS reduced opioid consumption. In addition, two regional anesthetic techniques, the transversus abdominis plane (TAP) block and the quadratus lumborum block (QLB), have been shown in multiple studies to reduce post-operative opioid consumption after CS. A recent randomized controlled trial showed that QLB is more effective in reducing morphine consumption post-CS compared to TAP. No randomized controlled trial to date, however, compared the analgesic effect of QLB with infiltration of the wound after CS. The objective of the study is to compare the analgesic effect of QLB type 2 with wound infiltration after CS.

Timeline

Start
2019-08-28
Primary completion
2020-05-12
Completion
2020-05-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Levobupivacaine Other / unclassified 0.18 % Other
Subject Levobupivacaine Other / unclassified 0.25 % Other

Indications