drugset / Trial / NCT04014803
Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion
Phase 4
Recruiting
3500 enrolled
Samsung Medical Center
Chonnam National University Hospital · collabChung-Ang University Hospital · collabChungbuk National University Hospital · collabChungnam National University Hospital · collabDankook University · collabEwha Womans University Seoul Hospital · collabGachon University Gil Medical Center · collabGyeongsang National University Hospital · collabIncheon St.Mary's Hospital · collabInje University Ilsan Paik Hospital · collabKeimyung University Dongsan Medical Center · collabKonkuk University Chungju Hospital · collabMediplex Sejong Hospital · collabSejong General Hospital · collabSeoul St. Mary's Hospital · collabSoonchunhyang University Hospital · collabWonju Severance Christian Hospital · collabWonkwang University Hospital · collabYeungnam University Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a prospective, open label, two-arm, randomized multicenter trial to evaluate the efficacy and safety of aspirin plus prasugrel as compared with aspirin plus clopidogrel in patients undergoing elective percutaneous coronary intervention with drug eluting stents for complex coronary lesions.
Timeline
- Start
- 2020-01-13
- Primary completion
- 2027-06-30
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clopidogrel | Small molecule | 75 mg | — |
| Comparator | Prasugrel | Small molecule | 5 mg | — |
| Comparator | Prasugrel | Small molecule | 10 mg | — |
| Comparator | Aspirin | Small molecule | 100 mg | — |