drugset / Trial / NCT04026256
Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
Phase 4
Completed
37 enrolled
Massachusetts General Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · collab
RandomizedParallel-groupSingle-blindOther
Summary
The purpose of this study is to examine, via iliac crest bone biopsies, the mechanism of combined teriparatide and denosumab on the bone of postmenopausal osteoporotic women after 3 months of treatment.
Timeline
- Start
- 2019-09-02
- Primary completion
- 2022-04-18
- Completion
- 2022-04-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Denosumab | Monoclonal antibody | — | Subcutaneous |
| Comparator | Teriparatide | Protein / enzyme biologic | — | Subcutaneous |