drugset / Trial / NCT04026464
Addition of Acetaminophen in Standard PDA Management
RandomizedParallel-groupSingle-blindTreatment
Summary
Patent ductus arteriosus is a common morbidity in preterm infants and management of PDA varies among neonatologist. The investigators are conducting a randomized controlled trial to determine the rates of initial patent ductus arteriosus (PDA) closure after completion of a first treatment course.
Timeline
- Start
- 2021-04
- Primary completion
- 2021-05-12
- Completion
- 2021-05-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 15 mg/kg | Oral |
| Comparator | Ibuprofen | Small molecule | 5 mg/kg | Intravenous |