drugset / Trial / NCT04030767

Evaluating Lip Repositioning for the Treatment of Excess Gingival Display With and Without Pretreatment With Botox

NCT04030767

Phase 1 Unknown 22 enrolled Cairo University
RandomizedParallel-groupSingle-blindTreatment

Summary

Since the introduction of the lip repositioning procedure by a number of modifications to the technique have been introduced. All these modifications were made to prevent the main complication of lip repositioning surgeries 'relapse'. Relapse was found to occur in 8% of the cases treated . Botox injections have been suggested as a possible treatment for cases with relapse Botox acts by blocking muscular activity, however, Botulinum toxin technique has a transitory effect (6-7 months). . By combining Botox as a pretreatment and lip repositioning surgery, Botox injections maybe a useful adjunct in improving and stabilizing the results of achieved, by paralyzing the muscles during the healing period. There are no studies, to the investigator's knowledge, exploring the use of botox combined with lip repositioning to decrease muscle pull and therefore decrease the relapse.

Timeline

Start
2019-09-20
Primary completion
2020-09-20
Completion
2022-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Botulinum toxin Protein / enzyme biologic

Indications