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drugset / Trial / NCT04049630

Clinical Trial Evaluating the Safety and Efficacy of Levamisole in Loa Loa Microfilaremic Patients

NCT04049630 ↗

Phase 2 Completed 255 enrolled Programme National de Lutte contre l'Onchocercose, Republic of the Congo

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study aims at evaluating the safety and efficacy of levamisole in patients with loiasis infection.

Timeline

Start: 2021-01-16
Primary completion: 2021-04-24
Completion: 2021-07-15

Publications

Campillo JT, Bikita P, Hemilembolo M, Louya F, Missamou F, Pion SDS, Boussinesq M, Chesnais C. Safety and Efficacy of Levamisole in Loiasis: A Randomized, Placebo-controlled, Double-blind Clinical Trial. Clin Infect Dis. 2022 Aug 24;75(1):19-27. doi: 10.1093/cid/ciab906.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Levamisole	Small molecule	1 mg/kg	—
Subject	Levamisole	Small molecule	1.5 mg/kg	—
Subject	Levamisole	Small molecule	2.5 mg/kg	—

Indications