drugset / Trial / NCT04051567
Low-dose Aspirin for Prevention of Adverse Pregnancy Outcomes in Twin Pregnancies
Phase 4
Unknown
425 enrolled
Ministry of Science and Technology of the People´s Republic of China
Chongqing Medical Center for Women and Children · collabPeking University Third Hospital · collab
RandomizedParallel-groupTriple-blindPrevention
Summary
Twin pregnancies are associated with increased risk of perinatal adverse outcomes , including preeclampsia , fetal growth restriction , preterm premature rupture of membranes and preterm birth. Low-dose aspirin was recommend by American College of Obstetricians and Gynecologists (ACOG) during pregnancy. In this trial, the investigators suppose that aspirin used in twin-pregnancies could improve adverse pregnancy outcomes.
Timeline
- Start
- 2018-11-01
- Primary completion
- 2020-06-01
- Completion
- 2020-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 100 mg | — |