drugset / Trial / NCT04071574

Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility

NCT04071574

Phase 1/2 Completed 200 enrolled Lebanese University
Non-randomizedParallel-groupOpen-labelHealth-services research

Summary

The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A" gonadotropins alone, "B" short GnRH agonist, "C" multiple-dose GnRH antagonist, "D" long GnRH agonist and "E" combined protocol of GnRH antagonist and agonist) and the outcomes of ICSI. This comparative study will help clinicians to select the relevant protocol of ovarian stimulation related to the female infertility disorders.

Timeline

Start
2018-02-01
Primary completion
2019-08-22
Completion
2023-05-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cetrorelix Other / unclassified 0.25 mg Subcutaneous
Comparator Ganirelix Protein / enzyme biologic 0.25 mg Subcutaneous
Comparator Menopur Protein / enzyme biologic 150 iu
Comparator Menopur Protein / enzyme biologic 225 iu
Comparator Triptorelin Other / unclassified 0.1 mg
Comparator human chorionic gonadotropin Protein / enzyme biologic 10000 iu