drugset / Trial / NCT04072640
Three Induction Treatments on Cryptococcal Meningitis
Phase 0
Unknown
120 enrolled
First Affiliated Hospital of Zhejiang University
Wenzhou Central Hospital · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
Three induction treatment strategies \[ voriconazole +5FC vs. amphotericin deoxycholate (0.4-0.5 mg/kg/d)+5FC vs. amphotericin deoxycholate (0.7-1.0 mg/kg/d)+5FC \] for HIV-infected patients with cryptococcal meningitis were compared.
Timeline
- Start
- 2021-01-25
- Primary completion
- 2022-07-31
- Completion
- 2022-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Voriconazole | Small molecule | 200 mg | Intravenous |
| Subject | amphotericin B deoxycholate | Unknown | 0.4 mg/kg | — |
| Subject | amphotericin B deoxycholate | Unknown | 0.7 mg/kg | — |