drugset / Trial / NCT04083950
Induction of Gut Permeability by an Oral Vaccine
NaSingle-groupOpen-labelBasic science
Summary
This study evaluates the effect of an oral typhoid vaccine on disruption of the intestinal barrier and response of the immune system. Intestinal and whole-body responses will be measured in all participants before and after the vaccine.
Timeline
- Start
- 2019-12-04
- Primary completion
- 2022-01-31
- Completion
- 2026-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 325 mg | Oral |
| Subject | Ty21a | Vaccine | — | Oral |