drugset / Trial / NCT04099836

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

NCT04099836 ↗

Phase 2 Terminated 7 enrolled Duke University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate the safety and efficacy of giving atezolizumab combined with bevacizumab in patients with stage 4 epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC) whose cancer has gotten worse while receiving osimertinib.

Timeline

Start
2020-07-09
Primary completion
2022-11-13
Completion
2023-06-15

Outcome

Outcome not reported

Stopped (Enrollment): “low accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1200 mg Intravenous
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous