drugset / Trial / NCT04104438
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant
RandomizedSequentialOpen-labelTreatment
Summary
This is a study to help understand how well new combinations of immunosuppressive medications (medications that weaken your immune system to prevent your body from rejecting the transplanted liver) work compared to standard immunosuppressive medications after your liver transplant. Also the study will assess how safe the new combination of immunosuppressive medicines are and if there are any changes in how your kidneys work after taking these medicines.
Timeline
- Start
- 2021-01-15
- Primary completion
- 2024-09-30
- Completion
- 2024-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Basiliximab | Monoclonal antibody | 20 mg | Intravenous |
| Comparator | Everolimus | Small molecule | 1 mg | Oral |
| Comparator | Tacrolimus | Small molecule | — | Oral |
| Comparator | mycophenolic acid | Small molecule | — | — |
Indications
No indication recorded.