drugset / Trial / NCT04116528
Opiate Suicide Study in Patients With Major Depression
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To explore whether intravenous ketamine followed by buprenorphine produces more rapid and sustained anti-suicidal effects than ketamine followed by placebo, investigators will conduct a single study that will take approximately 2.5 years to complete. 60 subjects (60 infusions) or approximately 24 infusions per year.
Timeline
- Start
- 2020-08-01
- Primary completion
- 2025-04-28
- Completion
- 2025-04-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Buprenorphine | Other / unclassified | 0.2 mg | Other |
| Comparator | Buprenorphine | Other / unclassified | 0.8 mg | Other |