drugset / Trial / NCT04135014

Combination With Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Patients

NCT04135014 ↗

RandomizedParallel-groupSingle-blindTreatment

Summary

Children tend to anxiety and even fear before survey. And this kind of anxiety will not result in the forced induction of anesthesia, but also may increase the incidence of postoperative agitation in children, even lead to postoperative behavior changes.Currently,Oral midazolam or intranasal dexmedetomidine alone is commonly used as a preoperative regimen, but the clinical effects of each single-use are not satisfactory. In the investigators' study,the researchers conducted the current study to investigate whether dexmedetomidine combined with midazolam can increase the rate of satisfactory anesthesia induction in pediatric patients and achieve better sedative effect.

Timeline

Start
2019-10-25
Primary completion
2020-10
Completion
2020-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 1 ug/kg Intranasal
Subject Dexmedetomidine Other / unclassified 2 ug/kg Intranasal
Comparator Midazolam Small molecule 0.5 mg/kg Oral

Indications