drugset / Trial / NCT04135807
Implantable Microdevice In Primary Brain Tumors
NaSingle-groupOpen-labelDiagnostic
Summary
This pilot study will assess the safety and feasibility of using an implantable microdevice to measure local intratumor response to chemotherapy and other clinically relevant drugs in malignant brain tumors. * The device involved in this study is called a microdevice. * The drugs used in this study will only include drugs already used systemically for the treatment of gliomas.
Timeline
- Start
- 2020-03-03
- Primary completion
- 2028-01-21
- Completion
- 2028-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abenaciclib | Unknown | — | — |
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Everolimus | Small molecule | — | — |
| Subject | Irinotecan | Small molecule | — | — |
| Subject | Lapatinib | Small molecule | — | — |
| Subject | Lomustine | Small molecule | — | — |
| Subject | Osimertinib | Small molecule | — | — |
| Subject | Temozolomide | Small molecule | — | — |