drugset / Trial / NCT04143685
Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes
RandomizedParallel-groupOpen-labelTreatment
Summary
This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes. Participants will be randomized to receive either oral misoprotsol every four hours until going into labor, or intravenous oxytocin in increasing dose.
Timeline
- Start
- 2019-12-01
- Primary completion
- 2021-08-01
- Completion
- 2021-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Misoprostol | Other / unclassified | 50 ug | Oral |
| Comparator | Oxytocin | Peptide | 10 iu | Intravenous |