drugset / Trial / NCT04143685

Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes

NCT04143685

Unknown 200 enrolled sammour.rami
RandomizedParallel-groupOpen-labelTreatment

Summary

This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes. Participants will be randomized to receive either oral misoprotsol every four hours until going into labor, or intravenous oxytocin in increasing dose.

Timeline

Start
2019-12-01
Primary completion
2021-08-01
Completion
2021-10-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Misoprostol Other / unclassified 50 ug Oral
Comparator Oxytocin Peptide 10 iu Intravenous