drugset / Trial / NCT04147533

Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients with Chronic Myeloid Leukemia

NCT04147533

Phase 2 Active not recruiting 150 enrolled Masaryk University
NaSingle-groupOpen-labelOther

Summary

Evaluation of the efficacy and safety of withdrawal of tyrosine kinase inhibitors after previous two-step dose reduction in patients with chronic myeloid leukemia in deep molecular remission

Timeline

Start
2020-06-16
Primary completion
2026-06
Completion
2026-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule 200 mg
Subject Nilotinib Small molecule 400 mg
Subject dasatinib anhydrous Small molecule 40 mg