drugset / Trial / NCT04148820

One Versus Twice Daily Administration of Multiple Cardiovascular Agents in Patients With Ischemic Heart Disease

NCT04148820

Phase 4 Unknown 100 enrolled University of Roma La Sapienza
RandomizedParallel-groupOpen-labelTreatment

Summary

Patients with ischemic heart disease are often treated with multiple cardiovascular agents, including aspirin, statins, ezetimibe, Angiotensin Converting Enzyme (ACE) inhibitors or beta-blockers. Uncertainty about the optimal timing and clinical implications of administration of cardiovascular drugs still persists. The investigators will perform a pilot randomized trial to evaluate the efficacy and safety of a one daily administration of multiple drugs vs. twice daily administration.

Timeline

Start
2019-11-01
Primary completion
2021-10-31
Completion
2021-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule
Subject Atorvastatin Small molecule
Subject Perindopril Small molecule

Indications