drugset / Trial / NCT04149964
Postoperative Pain Control in Septum and Sinus Surgery
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients. Participants will be randomized like a flip of a coin to either the standard of care pain treatment of acetaminophen 325 mg as needed for pain plus opiates (acetaminophen/hydrocodone) as needed for breakthrough pain; OR to the study arm of acetaminophen 650 mg every 6 hours plus opiates (Oxycodone)as needed for breakthrough pain.
Timeline
- Start
- 2019-11-27
- Primary completion
- 2022-09-21
- Completion
- 2022-09-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 325 mg | Oral |
| Comparator | Acetaminophen | Small molecule | 650 mg | Oral |
| Comparator | Hydrocodone | Unknown | 7.5 mg | Oral |
| Background | Oxycodone | Other / unclassified | 5 mg | Oral |
Indications
No indication recorded.