drugset / Trial / NCT04150029

A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy

NCT04150029

Phase 2 Terminated 90 enrolled Novartis Pharmaceuticals
NaSequentialOpen-labelTreatment

Summary

This trial seeked to extend the preliminary findings of efficacy by evaluating MBG453 in combination with hypomethylating agents (HMA) and also Bcl-2 inhibitor venetoclax.

Timeline

Start
2020-09-01
Primary completion
2024-10-25
Completion
2024-10-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Sabatolimab Monoclonal antibody Intravenous
Background Azacitidine Other / unclassified Subcutaneous
Background Venetoclax Small molecule Oral