The Effect of Preoperative Aminophylline

Phase 1 Unknown 45 enrolled Beni-Suef University

RandomizedParallel-groupDouble-blindSupportive care

Summary

Several clinical studies and case reports suggested that aminophylline antagonizes the effects of diazepam , barbiturates , sevoflurane ,morphineand propofol.However, the available results from uncontrolled clinical settings make it difficult to quantify the specific effects of aminophylline on hypnotics and anesthetics

Timeline

Start: 2019-11
Primary completion: 2019-12
Completion: 2019-12

Publications

Kasim SA, Bahr MH, Abdelkader M, Rashwan DAE. The effect of preoperative aminophylline on the recovery profile after major pelvic-abdominal surgeries: a randomized controlled double-blinded study. BMC Anesthesiol. 2021 Apr 19;21(1):122. doi: 10.1186/s12871-021-01340-7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Aminophylline	Small molecule	2 mg/kg	Intravenous
Comparator	Aminophylline	Small molecule	4 mg/kg	Intravenous

Indications

No indication recorded.