drugset / Trial / NCT04157998

Ultrasound Assessment of Metoclopramide Effect on Gastric Volume in Cesarean Section

NCT04157998

RandomizedParallel-groupQuadruple-blindPrevention

Summary

the risk of aspiration pneumonitis during cesarean sections has significantly decreased. Nevertheless, precaution against gastric aspiration is still vital in patients in whom regional anesthesia contraindicated or in whom general anesthesia has to be administered (for example; during emergency cesarean delivery). The administration of intravenous anesthetics reduces the level of consciousness of a patient that compromises the protective reflexes of the upper airways. Moreover, a high level of sedation also reduces the tone of the LES (lower oesophageal sphincter). Both these situations predispose the risk of aspiration pneumonia in patients awaiting surgical interventions in supine position under general anesthesia

Timeline

Start
2019-11-01
Primary completion
2020-05-01
Completion
2020-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metoclopramide Small molecule 10 mg Intravenous

Indications