drugset / Trial / NCT04157998
Ultrasound Assessment of Metoclopramide Effect on Gastric Volume in Cesarean Section
RandomizedParallel-groupQuadruple-blindPrevention
Summary
the risk of aspiration pneumonitis during cesarean sections has significantly decreased. Nevertheless, precaution against gastric aspiration is still vital in patients in whom regional anesthesia contraindicated or in whom general anesthesia has to be administered (for example; during emergency cesarean delivery). The administration of intravenous anesthetics reduces the level of consciousness of a patient that compromises the protective reflexes of the upper airways. Moreover, a high level of sedation also reduces the tone of the LES (lower oesophageal sphincter). Both these situations predispose the risk of aspiration pneumonia in patients awaiting surgical interventions in supine position under general anesthesia
Timeline
- Start
- 2019-11-01
- Primary completion
- 2020-05-01
- Completion
- 2020-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metoclopramide | Small molecule | 10 mg | Intravenous |