drugset / Trial / NCT04170959

The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC

NCT04170959 ↗

Phase 2 Terminated 3 enrolled [email protected] Stand Up To Cancer · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

Study the effect of metformin when added to definitive locoregional radiotherapy on locoregional control and relapse rate in stage III non-small cell lung cancer patients receiving sequential chemoradiotherapy. Try to identify subsets of patients who derive maximum benefit of adding metformin to radiotherapy using innovative biomarkers.

Timeline

Start
2018-07-30
Primary completion
2021-01-08
Completion
2021-01-08

Outcome

Outcome not reported

Stopped (Business): “Loss of external funding”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule 500 mg Oral