drugset / Trial / NCT04170959
The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC
RandomizedParallel-groupOpen-labelTreatment
Summary
Study the effect of metformin when added to definitive locoregional radiotherapy on locoregional control and relapse rate in stage III non-small cell lung cancer patients receiving sequential chemoradiotherapy. Try to identify subsets of patients who derive maximum benefit of adding metformin to radiotherapy using innovative biomarkers.
Timeline
- Start
- 2018-07-30
- Primary completion
- 2021-01-08
- Completion
- 2021-01-08
Outcome
Outcome not reported
Stopped (Business): “Loss of external funding”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 500 mg | Oral |