drugset / Trial / NCT04171193
Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent
Phase 2
Unknown
30 enrolled
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
In this study the investigators will submit patients with treatment resistant depression to deep anesthesia with isoflurane to get 15 minutes of cortical burst suppression on electroencephalogram, once a week for six weeks. The follow up will be for 6 months. The aim is to evaluate the change in depression severity during the entire period.
Timeline
- Start
- 2019-12
- Primary completion
- 2020-09
- Completion
- 2020-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isoflurane | Other / unclassified | 2.4 % | Inhaled |
| Subject | Sertraline | Small molecule | — | Oral |