drugset / Trial / NCT04173338

Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma

NCT04173338 ↗

Phase 1 Terminated 9 enrolled Augusta University
NaSingle-groupOpen-labelTreatment

Summary

This study will combine cabozantinib with pemetrexed to treat patients with non-small cell lung cancer, urothelial cancer and advanced malignant mesothelioma. This study will test the safety of both drugs used together and see what effect (good or bad) it has no participants and their cancer.

Timeline

Start
2020-01-23
Primary completion
2022-03-28
Completion
2022-03-28

Outcome

Outcome not reported

Stopped: “Closed by IRB on 3/28/22”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 20 mg Oral
Subject Cabozantinib Small molecule 40 mg Oral
Subject Cabozantinib Small molecule 60 mg Oral
Subject Pemetrexed Small molecule 500 mg/m2 Intravenous