drugset / Trial / NCT04173403

A Long-term Study of AK102 in Patients With Hypercholesterolemia

NCT04173403

Phase 2 Completed 796 enrolled Akeso AD Pharma (Guangdong) · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II, open-label, non-controlled, extended study. The main objective of this study is to evaluate the long-term efficacy and safety of AK102 in combination with basic lipid-lowering therapy in patients with hypercholesterolemia. Subjects who have participated in the AK102 studies and have completed the last visit,and who, in the opinion of the investigator, are likely to benefit from continued treatment will be enrolled in this study.

Timeline

Start
2019-11-04
Primary completion
2023-02-17
Completion
2023-02-17

Drugs

EvaluationDrugModalityDoseRoute
Subject AK102 Monoclonal antibody 150 mg Subcutaneous
Subject AK102 Monoclonal antibody 300 mg Subcutaneous
Subject AK102 Monoclonal antibody 450 mg Subcutaneous
Background Ezetimibe Unknown

Indications