drugset / Trial / NCT04174612

AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance

NCT04174612

Phase 3 Unknown 172 enrolled GIMEMA Foundation
RandomizedParallel-groupOpen-labelTreatment

Summary

Prospective, multi-center, interventional, randomized, open clinical trial for the treatment of acute myeloid leukemia with FLT3 mutations customized upon the prognostic parameter PBC

Timeline

Start
2020-04-24
Primary completion
2022-12
Completion
2025-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cytarabine Small molecule 100 mg/m2
Subject Cytarabine Small molecule 1500 mg
Background Daunorubicin Small molecule 60 mg/m2
Background Midostaurin Small molecule 50 mg