drugset / Trial / NCT04182568

Nab-paclitaxel Compared With Docetaxel Followed by Anthracyclines and Cyclophosphamide in the Neoadjuvant Breast Cancer

NCT04182568

Phase 4 Unknown 100 enrolled Xijing Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is an open, multicenter, randomized controlled clinical trial for patients with newly diagnosed primary invasive breast cancer and clinical stage of T2 or above. The main purpose of this study is to evaluate the efficacy of dose-dense nab-paclitaxel compared with dose-dense docetaxel followed by anthracycline and cyclophosphamide in the treatment of HR positive and HER-2 negative breast cancer. The effectiveness and safety of the treatment.

Timeline

Start
2019-08-21
Primary completion
2021-08-21
Completion
2022-08-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Docetaxel Small molecule 100 mg/m2
Subject Paclitaxel Small molecule 260 mg/m2
Background Cyclophosphamide Other / unclassified

Indications