drugset

drugset / Trial / NCT04183387

Simvastatin in Uveitis

NCT04183387 ↗

Phase 2 Completed 50 enrolled Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology

RandomizedParallel-groupOpen-labelTreatment

Summary

The study evaluates anti-inflammatory effects and safety of simvastatin in non-infectious uveitis.

Timeline

Start: 2014-09
Primary completion: 2016-01
Completion: 2016-01

Publications

Shirinsky IV, Biryukova AA, Kalinovskaya NY, Shirinsky VS. Tear cytokines as potential biomarkers in non-infectious uveitis: post hoc analysis of a randomised clinical trial. Graefes Arch Clin Exp Ophthalmol. 2020 Aug;258(8):1813-1819. doi: 10.1007/s00417-020-04707-7. Epub 2020 May 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Simvastatin	Small molecule	40 mg	—

Indications