Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium

Summary

180 patients will be randomly divided into two groups 90 patients each using a computer-generated program. Group R: 90 patients will receive a Rivastigmine patch (4.6 mg) 24 h before the operation to 3 days post-operative Group M: 90 patients will receive Melatonin patch (7 mg) 24 h before the operation to 3 days post-operative Patients in the two groups will be compared regarding incidence and severity of delirium on postoperative days 1, 2 or 3 and 7

Timeline

Start

2019-11-18

Primary completion

2020-04-10

Completion

2020-05-01

Drugs

Indications