drugset / Trial / NCT04196946

Use of Intrathecal Analgesia in Appendectomy

NCT04196946

Completed 50 enrolled Nigde Omer Halisdemir University
RandomizedParallel-groupOpen-labelSupportive care

Summary

Acute appendicitis which is the most common cause of acute abdominal pain, is an acute inflammation of appendix vermiformis. Appendectomy operations can be performed as laparoscopic and open surgery. Addition of opioids to intrathecal local anesthetics to improve the quality of preoperative analgesia is an increasingly used method in recent years. The aim of this study is to compare bupivacaine-fentanyl and bupivacaine-alfentanil which are used intrathecally to create motor and sensory block. 50 volunteer patients who were diagnosed as appendicitis by laboratory tests and clinical diagnostic methods in general surgery clinic and classified as American Society of Anesthesiologists Classification I-II (ASA Class I-II) aged between 20-60 years scheduled for laparoscopic appendectomy operation, were included in this study. The patients were randomly assigned into two groups, Group I and Group II. Patients received spinal anesthesia with either 10 mg heavy bupivacaine (2 cc)+25 mcg fentanyl (0.5 cc) intrathecally (Group I, n=25) or 10 mg heavy bupivacaine (2 cc)+250 mcg alfentanil (0.5 cc) intrathecally (Group II, n=25).

Timeline

Start
2013-09-02
Primary completion
2015-09-02
Completion
2019-09-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Alfentanil Other / unclassified 250 ug Intrathecal
Subject Fentanyl Other / unclassified 25 ug Intrathecal

Indications

No indication recorded.