drugset / Trial / NCT04200248

A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular Degeneration

NCT04200248

Phase 2 Completed 94 enrolled Ribomic USA Inc
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a multicenter, active-controlled, double masked study assessing the safety, efficacy and durability of four monthly intravitreal (IVT) injections of RBM-007 monotherapy, and four monthly RBM-007 injections in combination with Eylea® dosed at every other month, compared to Eylea® monotherapy dosed at every other month in approximately eighty-one subjects with exudative age-related macular degeneration (AMD).

Timeline

Start
2019-12-02
Primary completion
2021-11-19
Completion
2021-12-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Aflibercept Protein / enzyme biologic Intravitreal
Subject RBM-007 Aptamer Intravitreal