Fixed-Dose Trial in Early Parkinson's Disease (PD)

Summary

The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early PD.

Timeline

Start

2019-12-13

Primary completion

2024-06-28

Completion

2024-06-28

Publications

• Pahwa R, Moro E, Espay AJ, Evans A, Saint-Hilaire M, Torres-Russotto D, Sanchez R, Leoni M, Duvvuri S, Combs C, Chang I, Tringali S, Boiser J, Zadikoff C, Antonini A. Fixed-Dose Tavapadon for Early Parkinson Disease: A Randomized Clinical Trial. JAMA Neurol. 2026 May 1;83(5):452-460. doi: 10.1001/jamaneurol.2026.0590.

Drugs

Indications