drugset / Trial / NCT04202835
ATG Plus PTCy vs ATG for CGVHD Prophylaxis
Phase 2
Active not recruiting
80 enrolled
McMaster University
Cell Therapy Transplant Canada · collabOzmosis Research Inc. · collabSanofi · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
A Randomized Pilot Trial to test the feasibility of comparing anti-thymocyte globulin plus post transplant cyclophosphamide with anti-thymocyte globulin alone to prevent chronic graft versus host disease.
Timeline
- Start
- 2020-10-14
- Primary completion
- 2024-05-18
- Completion
- 2026-02-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 50 mg/kg | Intravenous |
| Background | Thymoglobulin | Protein / enzyme biologic | 4.5 mg/kg | Intravenous |