drugset / Trial / NCT04204772
A Pilot Feasibility Study of Activated Charcoal in Healthy Volunteers
Phase 0
Completed
12 enrolled
Masonic Cancer Center, University of Minnesota
National Center for Advancing Translational Sciences (NCATS) · collab
RandomizedCrossoverOpen-labelSupportive care
Summary
This is a pilot study designed to test feasibility, tolerability, and safety of medical grade oral Activated Charcoal (AC) in 12 healthy volunteers. To determine the two most palatable and tolerable AC combinations. There will be a total of 4 combinations (2 AC doses and 2 solutions) in stage 1. Each participant will drink an assigned combination every day for 3 consecutive days (Monday, Tuesday, Wednesday, "M/T/W") and switch to a different assigned combination M/T/W the following week. AC solution assignments will be defined before the study using a balanced incomplete block design. Each subject will rate their experience using a 5-point scale every day for the 12 days they are on study.
Timeline
- Start
- 2020-01-22
- Primary completion
- 2021-03-31
- Completion
- 2021-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Activated Charcoal | Other / unclassified | 12 g | Oral |
| Subject | Activated Charcoal | Other / unclassified | 25 g | Oral |
Indications
No indication recorded.