Trial of Indomethacin in Chronic Pancreatitis

NCT04207060 ↗

Phase 1/2 Completed 27 enrolled Mayo Clinic National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The researchers are trying to find a way to slow down the progression of chronic pancreatitis (CP) and investigate the possibility of the long term treatment of this disease.

Timeline

Start: 2020-07-15
Primary completion: 2023-04-24
Completion: 2023-04-24

Publications

Han S, Vege SS, Hart PA, Saloman JL, Xu J, Li L, Cruz-Monserrate Z, Palermo TM, Hill R, Hao W, Yadav D, Topazian M, Conwell DL. Oral Indomethacin for Chronic Pancreatitis: Results From the PAIR Randomized Placebo-Controlled Trial. Clin Transl Gastroenterol. 2025 Sep 1;16(9):e00888. doi: 10.14309/ctg.0000000000000888.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Indomethacin	Small molecule	50 mg	Oral

Trial of Indomethacin in Chronic Pancreatitis

Summary

Timeline

Publications

Drugs

Indications