drugset / Trial / NCT04207931
Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
Phase 4
Recruiting
250 enrolled
Wake Forest University Health Sciences
The Skin of Color Society · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
Timeline
- Start
- 2018-04-30
- Primary completion
- 2026-11
- Completion
- 2027-03
Publications
- Background Sperling LC, Sau P. The follicular degeneration syndrome in black patients. 'Hot comb alopecia' revisited and revised. Arch Dermatol. 1992 Jan;128(1):68-74.
- Background Bin Saif GA, Ericson ME, Yosipovitch G. The itchy scalp--scratching for an explanation. Exp Dermatol. 2011 Dec;20(12):959-68. doi: 10.1111/j.1600-0625.2011.01389.x.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clobetasol | Small molecule | — | Topical |
| Comparator | Doxycycline | Small molecule | 100 mg | Oral |
| Comparator | Fluocinonide | Other / unclassified | — | Topical |
| Comparator | Minoxidil | Small molecule | 5 % | Topical |
| Comparator | Triamcinolone Acetonide | Other / unclassified | 7.5 mg/ml | Other |
| Comparator | betamethasone dipropionate | Small molecule | — | Topical |