drugset / Trial / NCT04221750
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors
Phase 3
Completed
114 enrolled
VA Office of Research and Development
Baylor College of Medicine · collabMichael E. DeBakey VA Medical Center · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
The continuing increase in prevalence of obesity in older adults including many older Veterans has become a major health concern. The clinical trial will test the central hypothesis that a multicomponent intervention consisting of lifestyle therapy (diet-induced weight loss and exercise training) plus metformin will be the most effective strategy for reversing sarcopenic obesity and frailty in older Veterans with obesity.
Timeline
- Start
- 2021-05-14
- Primary completion
- 2025-07-31
- Completion
- 2025-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 1500 mg | Oral |
Indications
No indication recorded.