drugset / Trial / NCT04225078
A Study to Evaluate the Effects of Loperamide (JNJ-289679) on Electrocardiogram Intervals in Healthy Adult Participants
RandomizedCrossoverQuadruple-blindDiagnostic
Summary
The purpose of this study is to assess the effects of loperamide on QT/ QT interval corrected for heart rate (QTc) intervals and electrocardiogram (ECG) morphology at therapeutic and supratherapeutic exposures in healthy participants.
Timeline
- Start
- 2020-01-17
- Primary completion
- 2021-12-21
- Completion
- 2022-01-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Loperamide | Small molecule | — | Oral |
| Subject | Moxifloxacin | Small molecule | — | Oral |
Indications
No indication recorded.